Respiratory Viral Infections in Immunocompromised Patients

This educational resource is dedicated to help increase awareness around the challenges associated with respiratory viral infections (RVI) in patients with primary or secondary immunodeficiency.

Explore discussions and topics that impact these vulnerable populations:

Risk factors
Case studies
Latest scientific data
Opinion leader insights
Treatment approaches
Prevention strategies

No two immunocompromised patients are the same. Recognize those at the highest risk:

IDENTIFY PATIENTS WITH PID AT RISK

Primary Immunodeficiency (PID)

PID results from genetic dysfunction of the immune system.¹

~250,000

patients are living with PID²

RISK FACTORS

Include asthma/COPD,³ chronic sinusitis,³ and bronchiectasis⁴

IDENTIFY PATIENTS WITH SID AT RISK

Secondary Immunodeficiency (SID)

SID results from medications such as chemotherapy, metabolic conditions, and infection.¹

~650,000
patients receive chemotherapy each year⁵
~23,000
receive HSCT/BMT6⁶
~40,000
receive solid organ transplants⁷

RISK FACTORS

Include hematologic malignancies,⁸ current treatment with chemotherapy,⁸ and solid organ transplants⁹

Images and descriptions are for illustrative purposes only

BMT, bone marrow transplant; COPD, chronic obstructive pulmonary disease; HSCT, hematopoietic stem cell transplant.

References

1. Raje N, Dinakar C. Immunol Allergy Clin North Am. 2015;35(4):599-623. 2. IDF Advocate: The National Newsletter of the Immune Deficiency Foundation; Fall 2007, Number 56. 3. Berger M, et al. Respir Med. 2017;132:181-188. 4. Jolles S. Clin Exp Immunol. 2014;178(Suppl 1):67-69. 5. Centers for Disease Control and Prevention. Preventing infections in cancer patients: information for health care providers. Accessed June 8, 2020. https://www.cdc.gov/cancer/preventinfections/providers.htm. 6. Health Resources & Services Administration. Donation and transplantation statistics. Accessed February 1, 2021. https://bloodstemcell.hrsa.gov/data/donation-and-transplantation-statistics. 7. Health Resources & Services Administration. Organ donation statistics. Accessed February 1, 2021. https://www.organdonor.gov/statistics-stories/statistics.html. 8. Na IK, et al. Eur J Haematol. 2019;102(6):447-456. 9. Paulsen GC, Danziger-Isakov L. Clin Chest Med. 2017;38(4):707‐726.